Material Safety Data Sheet for Pentafluorobenzoic Acid

Identification

Product Name: Pentafluorobenzoic Acid
Chemical Formula: C7HF5O2
CAS Number: 607-63-2
Synonyms: 2,3,4,5,6-Pentafluorobenzoic acid
Recommended Use: Research, organic synthesis, analytical chemistry
Supplier: Laboratory chemical providers, contact per local records
Contact Number (Emergency): Refer to local guidelines, usually provided by supplier

Hazard Identification

Classification: Acute toxicity (oral, dermal, inhalation), Skin irritation, Eye damage
GHS Label: Exclamation mark
Hazard Phrases: Harmful if swallowed, May cause skin and eye irritation
Precautionary Statements: Avoid contact with skin, eyes and clothing; Wash hands thoroughly after handling; Use personal protective equipment as required; Do not eat, drink or smoke near material
NFPA Rating: Health 2, Flammability 0, Instability 0

Composition / Information on Ingredients

Chemical Name: Pentafluorobenzoic Acid
Concentration: 99-100%
Molecular Weight: 214.07 g/mol
Impurities: Minimal content, check supplier analysis for trace elements

First Aid Measures

Inhalation: Move person to fresh air; Seek medical attention if symptoms continue; Keep person at rest
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes; Remove contact lenses if present; Consult physician
Skin Contact: Remove contaminated clothing; Wash affected area thoroughly with soap and water; Seek medical advice for persistent irritation
Ingestion: Rinse mouth; Do not induce vomiting; Get medical attention immediately; Never give anything by mouth to an unconscious person
Most Important Symptoms: Irritation, nausea, respiratory discomfort

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Strong water jets may spread the product
Hazardous Combustion Products: Hydrogen fluoride (HF), carbon oxides, toxic fumes
Protective Equipment: Firefighters use self-contained breathing apparatus and full protective gear

Accidental Release Measures

Personal Precautions: Wear gloves, goggles, lab coat, and suitable mask; Remove all ignition sources nearby; Provide adequate ventilation
Environmental Precautions: Prevent material from entering drains, sewers, or surface water; Contain spill using non-combustible absorbent
Methods for Clean Up: Sweep up and collect in suitable container for disposal; Clean contaminated floors with water and detergent; Dispose of according to local regulations

Handling and Storage

Handling: Work in a well-ventilated area; Avoid dust formation; Avoid contact with skin, eyes, and clothing; Keep containers closed when not in use; Practice good laboratory hygiene
Storage: Store in tightly closed containers; Keep in a cool, dry, and well-ventilated place; Keep away from incompatible materials such as strong bases and oxidizing agents
Incompatibilities: Strong bases, strong oxidizers, reducing agents

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established; Handle with precaution
Engineering Controls: Use chemical fume hood; Ensure proper ventilation at workplace
Personal Protection: Wear chemical-resistant gloves, safety goggles, lab coat; If dust forms, use particulate filter respirator
General Hygiene: Do not eat, drink, or smoke while using this product; Wash hands after handling

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless or faint chemical odor
Melting Point: 187–190°C
Boiling Point: Decomposes above 230°C
Solubility: Slightly soluble in water, soluble in organic solvents like acetone, ether
pH: Acidic in aqueous solution
Vapor Pressure: Not significant at room temperature
Density: 1.72 g/cm³ at 25°C
Flash Point: Not flammable
Partition Coefficient: Log Kow: estimated 2.3

Stability and Reactivity

Chemical Stability: Stable under normal conditions of use and storage
Reactivity: Not reactive under recommended use conditions
Hazardous Reactions: May react with strong bases or oxidizers; Avoid contact with alkali
Decomposition: Releases hydrogen fluoride and carbon oxides at high temperatures
Polymerization: No hazardous polymerization observed

Toxicological Information

Acute Toxicity: Harmful if swallowed; LD50 (oral, rats) data limited
Skin Corrosion/Irritation: Causes mild to moderate skin irritation
Eye Damage/Irritation: Causes eye irritation
Inhalation: May cause respiratory tract irritation; Data on chronic effects limited
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No reliable data available; Not listed by IARC, NTP, or OSHA
Sensitization: No data demonstrating sensitization
Other Effects: Prolonged or repeated exposure may lead to organ effects; Use strict laboratory safety measures

Ecological Information

Ecotoxicity: No definitive aquatic toxicity data; Avoid discharge into environment
Persistence and Degradability: May persist in environment due to fluorinated structure
Bioaccumulation Potential: Fluorinated aromatic compounds tend to bioaccumulate
Mobility in Soil: Unknown, but likely limited by low water solubility
Other Adverse Effects: Avoid release to surface waters to prevent possible long-term impact

Disposal Considerations

Waste Disposal: Collect and place in appropriate labeled waste container; Dispose of through authorized chemical disposal enterprise
Contaminated Packaging: Rinse thoroughly; Dispose as chemical waste
Legal Requirements: Follow local, regional, and national guidelines for incineration or safe landfill

Transport Information

UN Number: Not classified as dangerous for transport
Transport Hazard Class: Not regulated
Packing Group: Not assigned
Environmental Hazards: Not designated as hazardous to the environment
Special Precautions: Prevent container damage during transport; Ensure container labeling and closure

Regulatory Information

TSCA Status: Listed
DSL/NDSL (Canada): Confirm with supplier
REACH Registration (Europe): Check with European suppliers
OSHA: Considered non-hazardous as per GHS classification guidelines
SARA Title III, Section 313: Not listed
Other Regulations: Use, import, and disposal may have additional requirements depending on state and local laws