Material Safety Data Sheet: P-Treoctylphenol (Ptop)

Identification

Product Name: P-Treoctylphenol
Chemical Name: 4-(1,1,3,3-Tetramethylbutyl)phenol
Synonyms: p-Octylphenol
CAS Number: 140-66-9
Molecular Formula: C14H22O
Recommended Use: Industrial chemical, surfactant production, plastic additive
Supplier Details: Manufacturer or distributor contact, typically found on the shipping package or product label

Hazard Identification

Hazard Classification: Harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation, suspected of damaging fertility
Signal Word: Warning
Hazard Statements: Toxic to aquatic life with long lasting effects, may cause an allergic skin reaction, flammable vapors
Precautionary Statements: Avoid breathing vapor or spray, wear protective gloves and eye protection, wash thoroughly after use, keep away from open flames and hot surfaces

Composition / Information on Ingredients

Chemical Name: P-tert- Octylphenol
CAS Number: 140-66-9
Concentration: 99–100%
Impurities: Minimal; trace amounts of unreacted phenol possible in certain lots, check batch certificate
Other Components: No relevant non-hazardous components present in commercial grades

First Aid Measures

Inhalation: Move exposed person to fresh air immediately, monitor for breathing difficulties, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, immediately wash skin with soap and water for no less than 15 minutes, consult medical attention if irritation continues
Eye Contact: Rinse eyes with plenty of clean water for several minutes, lifting upper and lower eyelids, obtain medical attention for persistent pain or redness
Ingestion: Rinse mouth with water, do not induce vomiting, drink water if the person is fully conscious, seek prompt medical advice
Note to Physician: Treat symptomatically, monitor for allergic reactions, respiratory distress, or chemical burns

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam; water spray for cooling containers
Unsuitable Media: Direct water jet may spread chemical, avoid excessive runoff
Specific Hazards: Will emit toxic fumes under fire conditions, risk of container rupture in intense heat
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective clothing to prevent contact with skin and eyes
Special Procedures: Move unaffected containers away from fire area, use water mist to cool exposed surfaces and minimize vapor formation

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ensure proper ventilation, use personal protective equipment appropriate for handling chemical spills
Environmental Precautions: Prevent from entering waterways or sewers, report major spills to appropriate authorities
Spill Cleanup Methods: Absorb with inert material like sand, collect in suitable container for disposal, clean contaminated area with detergent and water, ventilate area thoroughly

Handling and Storage

Handling: Use only in well-ventilated areas, avoid inhalation and direct contact with product, wear protective gloves and goggles, refrain from eating or smoking during handling
Storage Conditions: Store in original tightly-closed container, in a cool, dry, well-ventilated place, away from strong acids, oxidizers, or strong bases
Incompatible Materials: Strong oxidizing agents, acidic or alkaline compounds, sources of ignition
Additional Safeguards: Post warning signs, keep emergency showers and eyewash stations nearby, maintain good housekeeping practices to prevent spills

Exposure Controls and Personal Protection

Occupational Exposure Limits: No occupational exposure limit assigned, use industrial hygiene testing if exposure suspected
Engineering Controls: General mechanical ventilation required, local exhaust recommended for bulk or frequent use
Personal Protection: Industrial goggles, chemical-resistant gloves (nitrile or neoprene), long-sleeved clothing, face shield or respirator in concentrated vapor situations
Hygiene: Wash hands thoroughly after handling, do not take contaminated clothing home, use skin lotion to prevent dryness
Environmental Controls: Techniques to capture or scrub vapors, spill trays or secondary containment around storage areas

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Distinct phenolic scent
Boiling Point: 279°C (approximate)
Melting Point: 85°C
Flash Point: 121°C (open cup)
Vapor Pressure: Low at room temperature
pH: Not applicable (neutral, non-aqueous)
Solubility: Practically insoluble in water, miscible with organic solvents
Density: Approximately 0.90 g/cm³
Viscosity: Moderate at ambient temperature, increases at low temperature
Partition Coefficient (log Kow): About 5.6 indicating significant bioaccumulation potential
Auto-Ignition Temperature: 425°C

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Hazardous Reactions: May react vigorously with strong oxidizing agents, acids, or alkalis
Conditions to Avoid: High heat, open flame, prolonged exposure to light
Hazardous Decomposition Products: Phenolic fumes, carbon monoxide, carbon dioxide, possibly toxic organic compounds during fire or decomposition
Polymerization: Will not occur under standard conditions

Toxicological Information

Acute Toxicity: Oral LD50 (rat): roughly 1800 mg/kg, may cause moderate toxicity if swallowed
Skin Corrosion/Irritation: Prolonged or repeated contact can cause irritation, possible dermatitis
Eye Damage/Irritation: Can cause significant eye irritation or conjunctivitis
Respiratory Sensitization: Vapors may irritate nasal passages, throat, and lungs at high concentration
Chronic Exposure Risks: Suspected reproductive toxin, OECD studies suggest interference with endocrine function
Other Effects: Not classified as a known carcinogen, but precaution needed due to endocrine-related effects
Medical Conditions Aggravated by Exposure: Existing skin, respiratory, or allergic conditions

Ecological Information

Aquatic Toxicity: Highly toxic to aquatic organisms, significant adverse long-term effects possible
Bioaccumulative Potential: High; compound persists and concentrates in aquatic life due to log Kow around 5.6
Mobility in Soil: Binds to organic matter, low water solubility, leaching not significant under typical ground conditions
Degradability: Biodegradable under certain conditions, rate and completeness vary depending on biological activity within exposed environment
Other Adverse Effects: Poses long-term risk to aquatic communities, exposure should be managed to prevent release

Disposal Considerations

Waste Generation: Collect residues in appropriate containers, minimize generation where possible
Disposal Methods: Send to licensed chemical disposal or incineration facility, never discharge to surface drains or natural waterways
Contaminated Packaging: Dispose of in accordance with local, regional, and national regulations, containers should be thoroughly cleaned prior to recycling or disposal
Regulatory Precautions: Handle as hazardous industrial waste; consult local rules for classification and disposal limits

Transport Information

UN Number: 3082 (Environmentally Hazardous Substance, Liquid, N.O.S.)
UN Proper Shipping Name: Environmentally hazardous substance, liquid, n.o.s. (contains p-tert-Octylphenol)
Transport Hazard Class: 9 (Miscellaneous Dangerous Substances)
Packing Group: III
Environmental Hazards: Marine pollutant, mark packages accordingly for sea transport
Special Transport Precautions: Secure tightly to prevent leaks, inspect containers periodically during transport, emergency procedures accessible to handlers

Regulatory Information

Global Chemical Inventories: Listed on TSCA (US), EINECS/ELINCS (Europe), DSL (Canada), AICS (Australia), ENCS (Japan)
Labeling Requirements: GHS signal word, hazard pictograms, relevant hazard and precautionary statements must appear on label
Restrictions: Use is regulated by EU REACH (annex XIV/sunset list candidates), OSHA, and EPCRA in the USA for workplace and environmental protection
SARA Title III (USA): Not subject to Section 302/304, reportable under Section 313
California Proposition 65: Not currently listed, but endocrine disruptor warning recommended
Workplace Regulations: Employers provide hazard communication training, access to MSDS and chemical safety equipment for all staff in handling area