P-Tert-Butylphenol (PTBP): Insight and Outlook

Historical Development

Folks across the globe rarely think twice about the simple chemicals behind plastics, paints, and adhesives that hold our daily lives together. PTBP didn’t emerge by accident; chemists started synthesizing it early in the twentieth century, eager to find phenolic compounds that balanced function with cost. PTBP owes its commercial spark to the booming plastics and coatings industries post-World War II. With researchers looking for replacements for natural phenols, the discovery that tert-butyl substitution offered better mechanical and chemical resistance hit a sweet spot. By the 1950s, major chemical brands started rolling out PTBP at scale, fueling everything from new adhesives to innovations in rubber processing.

Product Overview

PTBP might not catch the public’s eye, but behind the scenes, it pulls plenty of weight in industrial circles. Chemists use this compound to make resins, surfactants, oil additives, and even specialty inks. Its molecular structure stands out: a phenol ring with a bulky tert-butyl group bats away reactive agents, giving PTBP much better durability than regular phenol. It’s this stability and versatility that make it the ingredient of choice when performance matters—paint that doesn’t peel, insulating materials that brave the elements, and adhesives that outlast the products they hold together.

Physical & Chemical Properties

Solid at room temperature, PTBP takes a crystalline or flaky form with an off-white appearance. It melts near 98°C, giving it some serious staying power during industrial processing. Not highly water-soluble, it finds company with organic solvents, which opens all kinds of doors for mixing and reacting in manufacturing lines. The tert-butyl group, sticking off the aromatic ring, stiffens it up against oxidation, acidity, and bases that might chew through lesser phenols. This same bulkiness dials up its performance as a stabilizer, letting companies count on their end products weathering rough handling or long storage. Flammability calls for a careful storage routine, which means most factories keep their PTBP in tightly sealed drums away from open flames and oxidizers.

Technical Specifications & Labeling

Supplier sheets for PTBP usually state purity, moisture, melting point, and heavy metal content. Top-grade samples hit over 99% purity with minimal impurities—a crucial fact for resin producers, since stray ions or water can lead to weak spots in cured products. Quality control teams look for labels conforming to standards like ASTM or GB/T, which track trace metals, phenol residues, and physical form. Labels flag key hazards, such as skin and eye irritation or flammability. Each drum or bag carries a batch number, manufacturing date, and recommended storage instructions to dodge heat and moisture.

Preparation Method

The classic way to make PTBP relies on reacting phenol with isobutylene or tert-butanol with solid acid catalysts. Acid-catalyzed alkylation forms a tight bond between the aromatic ring and tert-butyl group. Stirred reactors churn out product, and once the batch cools, crystallizers separate out PTBP from mother liquor and leftover byproducts. Rather than relying only on batch reactors, some big plants now run continuous lines for better yields, tighter control, and less waste. The biggest headaches still come from managing leftover acids and keeping phenol emissions in check, so most manufacturers invest in scrubbers and water treatment.

Chemical Reactions & Modifications

PTBP steps up as a building block for further chemical tweaks. It reacts with formaldehyde under controlled heat and pH to form resol or novolac resins, both critical for molding, laminates, or electronics. The hydroxyl group on PTBP’s ring gives it a leg up in condensation with aldehydes, making resin networks tighter and more chemically resistant. Companies also use PTBP as a precursor for surfactants: sulfonation adds watery compatibility, while etherification or esterification adds flexibility for different blends in lubricants and cleaning products. The tert-butyl group rarely budges, so it keeps the backbone stable during these reactions.

Synonyms & Product Names

PTBP goes by more than one name, depending on where you look: p-tert-butylphenol, 4-tert-butylphenol, and even para-tert-butylphenol on older labels. Some chemical houses market it under proprietary tradenames, but the CAS Number 98-54-4 keeps everyone communicating clearly. The synonym game can trip up buyers crossing borders, but industry veterans keep both chemical and trade names on inventory lists to avoid shipping delays or compliance snarls. Resins derived from PTBP also turn up under pharma codes or brand-specific acronyms, further proof that clear labeling is more than a bureaucratic checkbox.

Safety & Operational Standards

Ask anyone at a large chemical plant, safety protocols around PTBP require hands-on attention. PTBP may irritate skin and eyes, so gloves and goggles are standard on the factory floor. Dust and vapors from the solid can sneak into airways, so local exhaust and enclosed mixing vessels make a real difference in worker health. Fire departments insist on storing PTBP away from oxidizers and in fireproof cabinets to head off disaster, considering the solid’s flammable nature. Compliance officers check Material Safety Data Sheets regularly, making sure all hazard communication meets local laws and international shipping rules. Smaller facilities sometimes cut corners on ventilation; I’ve seen companies slapped with fines or forced shutdowns after routine inspections turned up violations, costing more than investing in basic controls to start with.

Application Area

PTBP’s reach spreads across adhesives, coatings, resins, and the rubber industry. Epoxy resin formulators swear by the compound to cure materials faster and boost mechanical properties for floor coatings and electronics. Rubber manufacturers lean on PTBP as a tackifier, ensuring layers stick during tire assembly or belting, and PTBP’s durability gives finished goods longer life in wet, hot, or chemically aggressive conditions. Printing ink makers tout PTBP for its ability to keep pigments dispersed and ink flowing smoothly without breakouts. Even oil and lubricant producers mix PTBP-based surfactants to control sludge, tackle acidity, and boost oil longevity. It’s not unusual to see PTBP blend into specialty textiles or flame retardant foam, where performance edges matter most.

Research & Development

PTBP hasn’t stopped evolving, as researchers keep exploring greener, more energy-efficient synthesis methods. Labs look for catalysts that slice down on acidic waste and cut water consumption—a push that also responds to rising regulatory heat. Some teams experiment with biobased feedstocks, like bio-isobutylene, trying to shrink the carbon footprint. PTBP’s utility as a precursor in functional resins prompts constant tweaks, such as adding new functional groups to the aromatic ring for next-generation adhesives or coatings with lower VOC emissions. I’ve followed university-industry partnerships testing new blends in 3D printing resins and medical adhesives, showing how even a widely known chemical can break new ground with a bit of fresh thinking. Open sharing of results through academic journals and patent filings helps manufacturers adapt quickly, staying ahead of demand and greener regulations.

Toxicity Research

Researchers have studied PTBP’s toxicity for decades, with most findings showing low acute toxicity in humans but some potential for skin and eye irritation. Studies with laboratory animals suggest limited but real risk for organ effects with high chronic exposure, which puts the spotlight on handling and environmental controls. Ecotoxicity data points to moderate risk for aquatic species—runoff from poorly managed factories or spills has led regulators to draw strict disposal and wastewater treatment guidelines. PTBP never enters food or medical-grade supplies without passing tough purity screens. In work settings, regular health monitoring and air quality checks make a big difference, based on real cases where workers developed rashes or respiratory discomfort from repeated contact or dust inhalation. That’s why most upstream suppliers invest in closed handling systems and spill response drills.

Future Prospects

Industrial demand for PTBP keeps tracking with global trends in construction, automotive, and electronics. As industries pivot toward sustainable products, companies face mounting pressure to find safer, cleaner synthesis routes and lower-toxicity alternatives where possible. Regulatory agencies expand their oversight as more toxicity studies get published, pushing companies to rethink waste streams and emission controls. The search for better catalysts and greener feedstocks continues to grow, boosted by government grants and rising consumer awareness. PTBP-based resins still offer the kind of performance engineers count on—high strength, chemical resistance, and durability. As applications in specialty plastics, next-gen composites, and advanced electronics expand, PTBP looks set to stay in the spotlight, provided companies keep raising their safety and environmental game. Looking forward, step changes in production efficiency and lower-impact chemistry could help the chemical remain viable, giving both industries and their customers confidence in the decades ahead.



What is P-Tert-Butylphenol (PTBP) used for?

Building Stronger Plastics and Adhesives

From my time working in a small plastics shop, I came to respect the things you can’t see. P-Tert-Butylphenol (PTBP) belongs on that list. This chemical pops up behind the scenes in epoxy resins, the kind that help hold together everything from aircraft parts to floor coatings. If you’ve mixed two resins and watched them harden in minutes, chances are PTBP had a role. It strengthens those resins, making final products that stand up to heavy use and constant stress.

Adhesive makers like PTBP, especially when producing phenolic adhesives. Decades ago, people counted on glue that refused to let go—be that in plywood, furniture, or packaging. PTBP became a clear choice for boosting the resilience and heat resistance of adhesives. Those glues bond fast, keep holding under high temperatures, and brush off exposure to oil or chemicals.

Everyday Uses—With Hidden Risks

PTBP also finds its way into some rubber products. Look at the soles of durable work boots or the inside of industrial hoses. Manufacturers want a tough rubber that resists cracking, ultraviolet light, and chemical spills. Adding PTBP makes the rubber less likely to turn brittle. That helps shoes last longer and keeps industrial gear running with fewer replacements.

On the electronics front, circuit board coatings often count on PTBP’s stabilizing effects. Those boards will see heat, solder, and daily use. The chemical provides an extra degree of confidence against early breakdown or humidity damage.

The Health Question No One Can Ignore

Now to the part that’s usually whispered, but shouldn’t be. PTBP can irritate skin, eyes, and the lungs. The European Chemicals Agency flagged PTBP as a substance of very high concern. Workers exposed through skin contact or inhalation report allergy symptoms more than you’d expect. PTBP is commonly found in some paints, lacquers, and inks, so the chance of exposure isn’t small.

Back at my old job, we wore gloves and washed hands like surgeons after touching resins with PTBP. At the time, safety data sheets felt more like a hassle until a rash or cough made the dangers real. Even low doses can be risky with repeated exposure. It’s not just something to worry about if you’re mixing drums in a factory. Lots of DIY epoxies and adhesives in hardware stores can list PTBP on the back, though many folks skip the fine print.

Better Choices for Tomorrow

Health experts now recommend shifting toward safer alternatives where possible. Some companies have started using epoxy resins that lean on less hazardous phenols or even switch to water-based versions—reducing both fumes and skin contact. Regulators in the EU and elsewhere keep pushing for stronger labeling and restrictions.

At the user level, gloves, good ventilation, and keeping products away from kids can help. But change really starts upstream, in the factories and labs where people choose what goes in the mix. The more people know about chemicals like PTBP, the more they can ask—or demand—safer solutions from the brands they buy and the workplaces they trust.

What are the typical physical and chemical properties of PTBP?

Getting to Grips with PTBP’s Physical Side

PTBP, short for para-tert-butylphenol, has shown up in places I never expected, especially after spending years dealing with synthetic resins and coatings. This chemical forms white or off-white flakes, and you’ll spot its faint, phenolic smell even before you touch it. PTBP melts at about 105°C, which makes it reasonably easy to handle in a lab or industrial setting—useful information if you’ve ever tried to blend or melt aromatic compounds. In water, PTBP mostly stays out. It dissolves better in organic solvents like ethanol, ether, or acetone, which lines up with its structure.

PTBP doesn’t just appear in production lines out of nowhere. It comes as a stable, heavy solid at room temperature—no powder floating in the air, no worries about dust explosions you sometimes get with other chemicals. That’s the kind of safety factor you want when storing barrels for months on end. Containers stay dry, far from sunlight and flames, because PTBP can irritate the skin and eyes. Storing it right protects both people and product quality.

Chemical Personality: What Makes PTBP Tick

PTBP stands out due to its phenol ring structure paired with a bulky tert-butyl group. That tert-butyl part doesn’t just look intimidating: It keeps the molecule from acting like ordinary phenol. Let’s say you’re running a resin reaction. Ordinary phenol would join up quickly and make things happen. PTBP slows things down, helping you control the process more precisely. That means people working with adhesives and coatings can fine-tune the final blend without racing against runaway reactions.

The chemical stability of PTBP matters in the real world. Resins made with it resist acids and moisture better than those made with plain phenol. For anyone working around water pipes, electrical insulation, or factory flooring, that increases lifetime and reliability. With phenols, oxidation is always in the back of your mind. PTBP can still oxidize, but the bulky tert-butyl group shields the active site, so it holds up longer.

Why These Properties Matter for Industry

Factories and labs count on PTBP across adhesives, epoxy resins, and hardener production. That melting range, the way it dissolves, and its managed reactivity allow engineers to build better, more durable materials. PTBP-based epoxy performs well under stress and aging. Floors in heavy industry, automotive brake pads, and electronics all get a bump in reliability.

As someone who used to track waste streams from polymer plants, I have seen the other side, too—washed-out tanks, dried film residues, and sky-high costs if storage goes wrong. PTBP’s solid form at ambient temperatures simplifies transport and handling, but it comes with its own environmental risks. Any industry using PTBP has to invest in solid chemical hygiene, not just for worker safety, but to keep residues from leaking out.

Pushing for Better Stewardship

There’s always a better way to handle chemicals. For PTBP, tougher rules around storage, personal protection, and effluent clean-up can limit its impact on people and the planet. Keeping up with new filtration and process recycling tech may help recover more PTBP from rinse-water and cleaning solutions. Industry groups keep updating best practices, but everyone—from plant manager to warehouse worker—needs to stay informed and push for improvements. Bringing real experience, straight talk, and hard-earned lessons into these conversations will drive safer and cleaner ways to use PTBP across all sectors.

How should P-Tert-Butylphenol be stored and handled safely?

P-Tert-Butylphenol—Why It Demands Respect

P-Tert-Butylphenol might not ring any bells outside chemical or industrial circles, but its risks feel real to anyone involved with storage or handling. I spent years in a plant environment where this compound turned up as a raw material, mostly for resin production. A slip-up always led to trouble. Strong skin irritation, eye damage, and dangerous inhalation risks made everyone treat it differently from ordinary materials.

How Proper Storage Cuts Risks

Direct sunlight heats up this compound. Besides raising volatility, high temperatures push vapors into the air and raise the chance of leaks. Our plant stuck to storing it in a cool, well-ventilated spot—away from incompatible chemicals like oxidizers. Every drum got labeled with clear hazard warnings. I learned the hard way that any spills would attack paint and eat away at certain plastics, so we only used containers lined with compatible coatings, never reusing random drums or containers.

We sometimes forgot about humidity in the warehouse. P-Tert-Butylphenol absorbs moisture and then forms crusts or clumps in the storage vessel. This increases handling troubles and can jam transfer lines. We added dehumidifiers on bad days, and it made a clear difference. Keeping containers tightly sealed helped too; it blocked both air and stray water.

Safe Handling—Keeping Workers Healthy

Most safety breakdowns happen at the human level. At our site, gloves rated for chemical exposure and splash goggles formed the base of every job. If folks ignored this, they’d end up red-faced at the nurse’s office. Resin projects sometimes needed full-face shields and chemical aprons—fast and simple solutions that paid off whenever spills hit. The right gloves—nitrile over latex—stopped us all from getting blistered hands by lunch.

Ventilation keeps vapors in check. We opened vents and used fume hoods for large batches. Airflow measured out regularly, and workers felt safer knowing they wouldn’t breathe in anything nasty. Respirators stepped in when working with open drums. Emergency showers and eyewash stations stood close by, which made everyone feel confident tackling tricky loads.

Planning for Emergencies

Spill response kits matter if someone drops a drum. Fast absorbents, chemical-resistant brooms and buckets, and clear step-by-step procedures meant we cleaned up quickly. Training became our secret weapon—frequent drills helped everyone stay calm. We ran regular reviews, tweaking our plans based on new incidents or feedback.

Disposal gets its own challenges. Local regulations spell out waste handling rules. We collected and labeled every bit of contaminated material, logging it before sending to certified hazardous waste sites. This documentation blocked fines and kept auditors off our backs.

Better Solutions: Prevention Over Reaction

Technological supports add another layer of protection. Automated liquid transfer pumps reduce spills from manual pouring. Digital sensors for leaks and vapors now play a role, giving early warning and saving headaches months later. Regular reviews and fresh training drills mean everyone remembers that this isn’t just another chemical—getting lazy invites disaster.

P-Tert-Butylphenol rewards vigilance with a safer workplace. After years around it, I learned that attention to detail always beats quick fixes. People go home healthy, and business rolls on without expensive fines or stoppages. That’s the lesson hard-earned from experience.

What industries commonly use PTBP in their products or processes?

Understanding PTBP in the Real World

PTBP, or para-tert-butylphenol, might not stand out in everyday conversation, but it shapes more products than most people realize. My years spent in technical writing and a stint in the chemical industry taught me that many core sectors owe their reliability and performance to what seems like an obscure compound. Most folks don’t recognize the name, but they sure run into what it helps create—from adhesive labels to glossy countertops.

The Ubiquity in Adhesive Formulations

Walk around any hardware store and you’ll spot countless glue bottles and industrial sealants. PTBP keeps these adhesives firm, flexible, and water-resistant. Manufacturers turn to it to add strength and stability. Think pressure-sensitive tapes—these have to stick through dampness and heat, and PTBP helps them pull it off. Fact is, it works well in bonding systems for automobiles, flooring, and electronics components. That consistent tackiness wouldn’t hold up in a modern factory without this compound behind the scenes.

The Backbone of Resins and Coatings

Paints, lacquers, and varnishes often rely on phenolic resins made with PTBP. During my research, I saw woodworking shops turn to coatings containing this compound because it leaves a durable finish that stands up to scratches, spills, and prolonged use. Furniture manufacturers and automotive companies both chase after glossy, long-lasting surfaces—PTBP helps deliver that hard-shell protection. In circuit boards and other electronics, resins based on this chemical shield sensitive parts from heat and chemical corrosion.

Rubber and Tire Manufacturing

I once spent a week shadowing a plant manager at a tire factory. Behind heavy machinery, I learned how PTBP enables rubber manufacturers to produce soles for shoes and tires for thousands of cars every day. It works as a curing agent, boosting the elasticity and heat resistance of synthetic rubber. This means car tires don’t just survive thousands of miles—they grip the road even in summer, thanks in part to this compound.

The Role in Plastics and Polymers

Plastic manufacturers add PTBP to their process for both stability and reliability, which is needed for containers, insulation, and high-load parts. For example, parts and housing in electrical equipment face constant stress from heat and moisture. With PTBP in the resin, these parts resist breaking down and protect wiring from faults or fires.

Specialty Chemicals and Future Uses

PTBP doesn't stop with glues, rubbers, or paints. Specialty chemical sectors use it for dyes, stabilizers, and intermediates for new synthesis. In the lab, I’ve seen researchers use it for developing water-resistant textiles or advanced surfactants. There’s a world of technical textiles—rainwear, boat covers, even fire-fighting suits—where water just beads off. That’s often the handiwork of surface treatments or coatings influenced by this chemical.

Thinking About Safer Practices

There’s a catch: PTBP’s effectiveness also brings environmental and health debates. Workers in resin plants deserve proper protections, and disposal practices impact waste streams. Industry leaders, under growing pressure from regulators and advocacy groups, push for safer handling and alternatives. Green chemistry initiatives, such as reducing phenolic compound use or recycling solvents, represent a positive step. Manufacturers, researchers, and regulators should keep the conversation open. Keeping production transparent supports safer products, cleaner air, and healthier communities.

Is P-Tert-Butylphenol hazardous to health or the environment?

P-Tert-Butylphenol in Daily Life

P-Tert-Butylphenol shows up in some places you might not expect. It takes a role in producing resins, adhesives, and even some coatings—products that people encounter at work or at home. This chemical isn’t something the average person recognizes, but it moves quietly through industrial and commercial supply chains. From what I’ve seen in occupational health reports, exposure to certain compounds like this one rarely gets much attention until a problem pops up.

Health Concerns Worth Knowing

This substance brings real issues for folks handling it directly. Just a splash on the skin can trigger redness or burns. A study from the National Institute for Occupational Safety and Health points to its ability to cause irritation not just on skin but also in the eyes and lungs if vapor or dust is around. Workers sometimes end up with rashes that don’t go away for weeks.

Some research highlights how P-Tert-Butylphenol passes through the skin, which only increases the risk. Allergic reactions pop up in documented case studies, with repetitive exposure leading to eczema or other stubborn conditions. The European Chemicals Agency lists the chemical as a skin sensitizer, so allergies get worse with more contact.

Environmental Impact at a Glance

Concerns stretch beyond personal health. Water samples near manufacturing facilities sometimes reveal traces of P-Tert-Butylphenol. It doesn’t break down quickly, so the compound can stick around in groundwater or soil. Fish and other aquatic species run the risk of being harmed, as shown in toxicity screens by the EPA. These organisms struggle to process it, which throws off natural balances in rivers and streams. My own time working with environmental field crews showed me how persistent chemicals can travel farther than you think when runoff hits heavy rain.

Regulation and Safer Practices

Agencies want to keep a close eye on how much of this chemical enters the workplace and ecosystems. OSHA puts limits on workplace exposure. Europe ranks P-Tert-Butylphenol among substances of concern, pushing for tighter rules. Companies must install proper ventilation and provide gloves, face shields, and protective clothing for those who work with it.

Labels and safety sheets don’t always get noticed or read. From what I've seen, even the best policies need hands-on training and real-world drills. Regular air monitoring and spill protocols back up formal rules, giving everyone on a site a fair shot at avoiding direct harm.

Pursuing Safer Solutions

Manufacturers can switch out chemicals or tweak their processes to reduce risk. Substituting safer alternatives sometimes takes upfront investment, but forward-thinking firms make the change for the sake of worker safety and long-term sustainability. Open conversations between management and staff help, laying out honest risks and practical ways to limit exposure.

Downstream, waste treatment plays a big part. Industries filter discharge and capture solvents before they escape into waterways. In some regions, new policies force companies to prove they’ve minimized any release of dangerous chemicals before permits get renewed.

Personal Responsibility in the Mix

Beyond industry, community awareness helps. Local officials can push for water testing near plants or start household hazardous waste days to keep leftovers out of landfills. Everyday people can demand stronger protections if they learn more about what’s in their backyard or workplace. Education gives people power, especially when a chemical lacks a household name but carries serious risks for those caught unaware.

P-Tert-Butylphenol (Ptbp)
Names
Preferred IUPAC name 2-(tert-Butyl)phenol
Other names 4-tert-Butylphenol
p-tert-Butylphenol
PTBP
para-tert-Butylphenol
4-(1,1-Dimethylethyl)phenol
p-t-Butylphenol
Pronunciation /ˌpiː tɜːt ˈbjuːtɪlˌfiːnɒl/
Preferred IUPAC name 2-tert-Butylphenol
Other names 4-tert-Butylphenol
p-tert-Butylphenol
PTBP
p-TBP
4-(1,1-dimethylethyl)phenol
Pronunciation /ˌpiː tɜːt ˈbjuːtɪlˌfiːnɒl/
Identifiers
CAS Number 98-54-4
Beilstein Reference 775874
ChEBI CHEBI:34762
ChEMBL CHEMBL156209
ChemSpider 22167
DrugBank DB14083
ECHA InfoCard ECHA InfoCard: 100.004.098
EC Number 202-679-0
Gmelin Reference 132568
KEGG C06588
MeSH D010759
PubChem CID 8051
RTECS number DO4375000
UNII U49R669FGT
UN number UN 2310
CAS Number 98-54-4
Beilstein Reference 1584977
ChEBI CHEBI:34770
ChEMBL CHEMBL16219
ChemSpider 14214
DrugBank DB14042
ECHA InfoCard 03b1b066-5c9e-4e94-a593-335b79d51c83
EC Number 202-679-0
Gmelin Reference 84135
KEGG C06532
MeSH D017614
PubChem CID 7917
RTECS number DO8575000
UNII 6RV4DL366D
UN number UN number: "UN 2430
Properties
Chemical formula C10H14O
Molar mass 150.22 g/mol
Appearance White flake or crystalline solid
Odor Distinct phenolic odor
Density 0.94 g/cm³
Solubility in water Slightly soluble
log P 2.8
Vapor pressure 0.03 mmHg (25°C)
Acidity (pKa) 10.2
Basicity (pKb) 10.6
Magnetic susceptibility (χ) -51.0e-6 cm³/mol
Refractive index (nD) 1.5290
Viscosity 12-16 cP (at 70°C)
Dipole moment 2.86 D
Chemical formula C10H14O
Molar mass 150.22 g/mol
Appearance White flaky crystal
Odor Phenolic
Density 0.959 g/cm³
Solubility in water slightly soluble in water
log P 2.8
Vapor pressure 0.03 mmHg (25°C)
Acidity (pKa) 11.1
Basicity (pKb) 10.15
Magnetic susceptibility (χ) -76.8e-6 cm³/mol
Refractive index (nD) 1.5330
Viscosity Viscosity: 10-12 cP (at 100°C)
Dipole moment 2.85 D
Thermochemistry
Std molar entropy (S⦵298) 146.3 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) −328.3 kJ·mol⁻¹
Std enthalpy of combustion (ΔcH⦵298) -4847.7 kJ/mol
Std molar entropy (S⦵298) 260.3 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) −308.6 kJ mol⁻¹
Std enthalpy of combustion (ΔcH⦵298) -5891.4 kJ/mol
Pharmacology
ATC code D11AX
Hazards
Main hazards Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
GHS labelling GHS02, GHS05, GHS07
Pictograms GHS02,GHS07,GHS08
Signal word Warning
Hazard statements Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of damaging fertility or the unborn child. Toxic to aquatic life with long lasting effects.
Precautionary statements P210, P261, P264, P271, P272, P273, P280, P301+P312, P304+P340, P305+P351+P338, P310, P330, P362+P364, P403+P233, P405, P501
NFPA 704 (fire diamond) 2-2-0
Flash point 113 °C
Autoignition temperature 522°C
Explosive limits 1.1–7%
Lethal dose or concentration LD50 oral rat 3,059 mg/kg
LD50 (median dose) LD50 (median dose): 2951 mg/kg (oral, rat)
NIOSH SF8400000
PEL (Permissible) 10 mg/m3
REL (Recommended) 10 mg/m³
IDLH (Immediate danger) No specific IDLH has been established for p-tert-Butylphenol (PTBP).
GHS labelling GHS02, GHS05, GHS07
Pictograms GHS02,GHS07,GHS08
Signal word Warning
Hazard statements H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
Precautionary statements P210, P261, P264, P271, P272, P280, P301+P312, P302+P352, P305+P351+P338, P321, P333+P313, P362+P364, P405, P501
NFPA 704 (fire diamond) 2-2-0
Flash point 113 °C
Autoignition temperature 540°C
Explosive limits Upper: 5.1%; Lower: 1.3%
Lethal dose or concentration LD50 oral rat 4000 mg/kg
LD50 (median dose) LD50 (median dose): 4000 mg/kg (oral, rat)
NIOSH US3730000
PEL (Permissible) PEL (Permissible exposure limit) for P-Tert-Butylphenol (PTBP) is 5 mg/m³ (OSHA, 8-hour TWA)
REL (Recommended) 10 mg/m³
IDLH (Immediate danger) Unknown
Related compounds
Related compounds Phenol
2,6-Di-tert-butylphenol
4-Cumylphenol
2-tert-Butylphenol
p-Phenylphenol
Related compounds Phenol
2-tert-Butylphenol
4-tert-Amylphenol
Bisphenol A
Nonylphenol