Bromopentafluorobenzene Material Safety Data Sheet

1. Identification

Product Name: Bromopentafluorobenzene
Chemical Formula: C6BrF5
Recommended Use: Intermediate for organic synthesis, used as a halogenated aromatic compound in research and industrial labs.
Manufacturer/Supplier: Names and contact details of the main suppliers in the region, including emergency contact numbers.
Synonyms: 1-Bromo-2,3,4,5,6-pentafluorobenzene, Pentafluorophenyl bromide
CAS Number: 434-90-2

2. Hazard Identification

GHS Classification: Skin irritant (Category 2), Eye irritant (Category 2A), Acute aquatic toxicity (Category 3)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, suspected damage to aquatic environment, harmful if inhaled or swallowed
Pictograms: Exclamation mark, Environmental hazard
Precautionary Statements: Avoid breathing vapors or dust, prevent release to the environment, wear protective gloves and eye protection

3. Composition / Information on Ingredients

Chemical Identity: Bromopentafluorobenzene
Concentration: 100% (pure substance for laboratory and industrial purposes)
CAS Number: 434-90-2
Other Components: Does not contain any known impurities or additives relevant for classification

4. First Aid Measures

Inhalation: Move to fresh air. Seek medical attention if symptoms continue, such as coughing or respiratory irritation.
Skin Contact: Wash thoroughly with soap and water. Remove contaminated clothing and wash before reuse. Medical advice recommended in case of reaction.
Eye Contact: Rinse gently with plenty of water for several minutes, lifting eyelids occasionally. Remove contact lenses if easy. Follow up with medical attention.
Ingestion: Rinse mouth with water. Do not induce vomiting. Obtain medical attention without delay if discomfort or symptoms occur.

5. Fire-Fighting Measures

Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder, or foam. Water spray for larger fires if suitable, but do not use a direct water jet.
Unsuitable Media: Avoid full water discharge from hoses to prevent chemical spread.
Specific Hazards: During fire, hazardous gases like hydrogen fluoride, bromine compounds, and carbon oxides can release.
Firefighting Advice: Firefighters wear self-contained breathing apparatus and chemical protective clothing. Cool containers with water to prevent pressure build-up and explosions.

6. Accidental Release Measures

Personal Precautions: Use personal protection recommended in section 8, keep unprotected personnel away, ventilate area.
Environmental Precautions: Prevent entry into sewers or waterways. Use absorbents to collect spillage; avoid release to the environment.
Methods for Cleanup: Contain loose material, collect with non-combustible absorbent (sand, earth), and store in chemical waste containers. Wash area with water after removal, taking water to the waste system.

7. Handling and Storage

Handling: Work in a well-ventilated area, avoid inhalation, ingestion, and skin contact. Use mechanical exhaust if necessary, and keep containers tightly closed.
Hygiene Requirements: Do not eat, drink, or smoke during use. Wash hands after handling, clean contaminated clothing before reuse.
Storage Conditions: Store in tightly sealed containers in a cool, dry, well-ventilated place. Keep away from sources of ignition and incompatible substances, like strong bases and oxidizers.
Incompatible Materials: Avoid strong alkalis, strong oxidizing agents, and reducing agents to prevent reactions.

8. Exposure Controls and Personal Protection

Occupational Exposure Limits: No established exposure limits, but minimize airborne levels as much as possible.
Ventilation: Use fume hoods and local extraction systems to keep vapor and mist concentrations low.
Hand Protection: Chemical-resistant gloves, such as nitrile or neoprene, change regularly to prevent permeation.
Eye Protection: Use safety goggles or a face shield.
Skin Protection: Wear lab coats or other chemical-resistant clothing, and use closed footwear.
Respiratory Protection: Use suitable respirators with filters for organic vapors if handling large amounts or if ventilation is inadequate.

9. Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Slightly aromatic, characteristic of halogenated benzenes
Melting Point: -27°C
Boiling Point: 151-153°C
Flash Point: 66°C (closed cup)
Evaporation Rate: Not determined
Flammability: Not considered highly flammable, but vapors may form explosive mixtures with air
Vapor Pressure: Approximately 12 mmHg at 25°C
Solubility: Insoluble in water, mixes with organic solvents (acetone, alcohol)
Density: 1.91 g/cm³ at 20°C
pH: Not applicable (not water soluble)

10. Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, does not self-react under normal temperatures and pressures.
Conditions to Avoid: High heat, direct sunlight, open flames, and sources of ignition.
Incompatible Materials: Oxidizers, strong alkalis, reducing agents, and aluminum or magnesium metals.
Hazardous Decomposition Products: Hydrogen fluoride, bromine fumes, and toxic carbon oxides may evolve if heated strongly or combusted.
Polymerization: Not known to occur under normal process circumstances.

11. Toxicological Information

Acute Toxicity: Expected to have low acute oral, dermal, and inhalation toxicity, but direct contact can irritate eyes, skin, and airways.
Skin Corrosion/Irritation: Causes skin irritation with prolonged exposure.
Serious Eye Damage/Irritation: May cause moderate eye irritation, especially with splashes.
Respiratory Sensitization: Vapors may irritate respiratory passages with coughing or sore throat after exposure.
Chronic Effects: No long-term human data, avoid chronic or repeated exposure because related compounds can sometimes cause organ effects.
Carcinogenicity: Not classified as a known carcinogen by IARC, NTP, or OSHA.

12. Ecological Information

Aquatic Toxicity: Harmful to aquatic life. Do not discharge into water.
Persistence and Degradability: Expected to degrade slowly in the environment because of stability of the aromatic fluorinated ring structure.
Bioaccumulation Potential: Has the potential to bioaccumulate in aquatic organisms due to high log Kow value.
Mobility in Soil: Does not move easily through soil, but will persist in sediments and organic-rich soils.
Other Adverse Effects: No major ozone depletion, but aquatic impact remains a concern.

13. Disposal Considerations

Waste Methods: Collect small quantities with absorbent and send to authorized chemical waste disposal company. Container and contents must be disposed of as hazardous waste.
Recycling: Not suitable for reclamation; avoid landfill or uncontrolled incineration.
Contaminated Packaging: Treat as hazardous, rinse thoroughly before recycling or follow facility guidance.
EPA Waste Codes: Contact local agencies for approved classification and safe handling rules.

14. Transport Information

UN Number: 3265 (for similar halogenated benzenes: check with current regulatory listing for precise number)
Proper Shipping Name: Halogenated aromatic liquid, n.o.s.
Hazard Class: 6.1 (toxic substances)
Packing Group: III
Marine Pollutant: Yes; avoid discharge to water during transit
Labeling Requirements: Toxic and environmental hazard labels for all international and domestic shipments

15. Regulatory Information

Global Inventories: Listed in TSCA (US), EINECS (EU), DSL (Canada), and other major inventories.
SARA Title III (Sections 302/313): Subject to regulations if stored above threshold quantities.
OSHA Status: Regulated hazardous material; safety training and chemical hygiene plan apply.
REACH Registration: Required for EU usage in significant quantities.
Other Regulations: Complies with GHS classification and regional labeling laws. Always check national and local environmental regulations for current legal requirements.